• Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis 

      Becker-Merok, Andrea; Kalaaji, Manar; Haugbro, Kaia; Nikolaisen, Cathrin; Nilsen, Kirsten; Rekvig, Ole Petter; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-10-24)
      This study investigated the overall clinical impact of anti-α- actinin antibodies in patients with pre-selected autoimmune diseases and in a random group of anti-nuclear antibody (ANA)- positive individuals. The relation of anti-α-actinin antibodies with lupus nephritis and anti-double-stranded DNA (anti-dsDNA) antibodies represented a particular focus for the study. Using a cross-sectional ...
    • The Influence of the 1997 Updated Classification Criteria for Systemic Lupus Erythematosus : Epidemiology, Disease Presentation, and Patient Management 

      Eilertsen, Gro Østli; Becker-Merok, Andrea; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2009)
      The influence of the 1997 updated classification criteria for systemic lupus erythematosus: epidemiology, disease presentation, and patient management. Eilertsen GØ, Becker-Merok A, Nossent JC. Department of Rheumatology, Medical School, University of Tromsø, 9037 Tromsø, Norway. gro.ostli.eilertsen@unn.no OBJECTIVE: The 1997 update of the American College of Rheumatology classification ...
    • Susceptibility for Lupus Nephritis by low copy number of the FCGR3B gene is linked to increased levels of pathogenic autoantibodies 

      Nossent, Johannes C; Becker-Merok, Andrea; Rischmueller, Maureen; Lester, Sue (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Low copy number (CN) of the FCGR3B gene reduces FCGR3B membrane expression on neutrophils and results in clearance of a smaller amount of immune complex. We investigated FCGR3B CN in relation to the clinical phenotype in a Caucasian SLE cohort (𝑛 = 107). FCGR3B CN was determined by three different qPCR parameter estimations (Ct−, Cy0, and cpD1) and confirmed by the FCGR2C/FCGR2A paralog ratio test. ...